opioid clinical trials - Search
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  2. Studies of opioid clinical trials
    National Center for Biotechnology Information
    Recent advances in the treatment of opioid use disorders–focus on long-acting buprenorphine formulations
    Oral methadone or sublingual buprenorphine are first-line medications for pharmacotherapy of opioid use disorders (OUDs). Three long-acting buprenorphine depot or implant formulations are currently available for the treatment of OUDs: (1) CAM 2038 (Buvidal)
    Author: Michael Soyka…
    Published: 2021/09/09
    Publication: World J P…
    National Center for Biotechnology Information
    The NIDA clinical trials network: evolving, expanding, and addressing the opioid epidemic
    Over the past two decades, the National Drug Abuse Treatment Clinical Trials Network (CTN), a program of the National Institute on Drug Abuse (NIDA), has expanded from the initial six Nodes to 16 Nodes, as a nationwide consortium of research scientists
    Author: Betty Tai, Ron…
    Published: 2021
    Publication: Addict Sc…
    PubMed
    Clinical Trials for Opioid Use Disorder
    This chapter describes recent clinical trials for opioid use disorder (OUD), an area that has rapidly accelerated in response to the opioid overdose crisis in the USA and newly appropriated funding. Trials involve a wide range of compounds including
    Author: Esther Blessing
    Published: 2020
    Keywords: Addiction; …
    National Center for Biotechnology Information
    Opioids and Chronic Pain: An Analytic Review of the Clinical Evidence
    We conducted an analytic review of the clinical scientific literature bearing on the use of opioids for treatment of chronic non-cancer pain in the United States. There is substantial, albeit not definitive, scientific evidence of the effectiveness
    Author: Stephen E. Na…
    Published: 2021
    Publication: Front Pai…
    PubMed
    Core outcomes set for research on the treatment of opioid use disorder (COS-OUD): the National Institute on Drug Abuse Clinical Trials Network protocol for an e-Delphi consensus study
    Background: A lack of consensus on the optimal outcome measures to assess the efficacy and effectiveness of interventions for the treatment of opioid use disorder (OUD) has hampered the pooling of research data for evidence synthesis and clinical
    Author: Niranjan S Kar…
    Published: 2021/01/28
    Keywords: A lack of co…
    ResearchGate
    Clinical Trials for Opioid Use Disorder
    This chapter describes recent clinical trials for opioid use disorder (OUD), an area that has rapidly accelerated in response to the opioid overdose crisis in the USA and newly appropriated funding. Trials involve a wide range of compounds including
    Author: Esther Blessin…
    Published: 2019/12/31
    DOI: 10.1007/164_2019…
    National Center for Biotechnology Information
    Research approaches for evaluating opioid sparing in clinical trials of acute and chronic pain treatments: IMMPACT recommendations
    Randomized clinical trials (RCTs) have demonstrated the efficacy of opioid analgesics for the treatment of acute and chronic pain conditions [8, 28] and for some patients, these medications may be the only effective treatment available. Unfortunately,
    Author: Jennifer S. Ge…
    Published: 2021/11/11
    DOI: 10.1097/j.pain.000…
    National Center for Biotechnology Information
    OPAL: a randomised, placebo-controlled trial of opioid analgesia for the reduction of pain severity in people with acute spinal pain—a statistical analysis plan
    Background Low back and neck pain are a leading cause of disease burden globally. Opioids are recommended in guidelines for acute low back and neck pain; however, there is a lack of compelling efficacy data to support this. Methods The OPAL trial is a
    Author: Caitlin MP Jon…
    Published: 2022
    Publication: Trials. 20…
     
  3. Medical School
    https://med.umn.edu/news/first-human-clinical...

    First-in-human clinical trial for a vaccine to treat opioid …

     
  4. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474991

    Recent advances in the treatment of opioid use …

  5. The New England Journal of Medicine
    https://www.nejm.org/doi/full/10.1056/NEJMr…

    Treatment of Opioid-Use Disorders - The New England …

    WEBJul 28, 2016 · This article provides an overview of the current treatment of opioid-related conditions, including treatments provided by general …

    • Author: Marc A Schuckit
    • Publish Year: 2016
  6. WebMD
    https://www.webmd.com/mental-health/addiction/...

    Clinical Trials for Opioid Dependence and Addiction

  7. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105960

    The NIDA clinical trials network: evolving, expanding, …

  9. JAMA Network
    https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2799201

    Clinical Trial Design Challenges and Opportunities for …

  10. The New England Journal of Medicine
    https://www.nejm.org/doi/full/10.1056/NEJMo…

    Diacetylmorphine versus Methadone for the Treatment of …

    WEBAug 20, 2009 · In an open-label, phase 3, randomized, controlled trial in Canada, we compared injectable diacetylmorphine with oral methadone maintenance therapy in patients with opioid dependence that was ...

  11. People also ask
    What are clinical trials for opioid use disorder?
    Clinical Trials for Opioid Use Disorder This chapter describes recent clinical trials for opioid use disorder (OUD), an area that has rapidly accelerated in response to the opioid overdose crisis in the USA and newly appropriated funding. Trials involve a wide range of compounds including cannabinoids and psychedelics, new and existing co …

    Clinical Trials for Opioid Use Disorder - PubMed

    pubmed.ncbi.nlm.nih.gov
    Is there a test for trial on for complex regional pain syndrome at this time?

    Dr. Mayank Saxena

    Doctor of Medicine (MBBS) · 1 years of exp

    No. There is no test that can diagnose complex regional pain syndrome till today. To diagnose this condition, we have to rule out other causes that may lead to similar symptoms and start the treatment accordingly.
    Q&A: Complex Regional Pain Syndrome
    microsoftstart.msn.com
    What are the predictors of chronic opioid treatment?
    However, when the analysis was restricted to opioid-naïve patients, the rate was 1.2%. The major statistical predictors of chronic opioid treatment were pre-operative opioid use, back pain, fibromyalgia, depression, and anxiety.

    Opioids and Chronic Pain: An Analytic Review of the Clinical Evidence

    ncbi.nlm.nih.gov
    What is the primary outcome of the opioid-related overdose trial?
    The trial groups were balanced within states according to urban or rural classification, previous overdose rate, and community population. The primary outcome was the number of opioid-related overdose deaths among community adults.

    Community-Based Cluster-Randomized Trial to Reduce Opioid Overdose

    nejm.org
    Feedback
  12. Clinical Trials at University of California Health
    https://clinicaltrials.ucbraid.org/opioid-use

    Opioid Use clinical trials at University of California Health - UC …

  13. PubMed
    https://pubmed.ncbi.nlm.nih.gov/31889218

    Clinical Trials for Opioid Use Disorder - PubMed

  14. Clinical Trials at UCSD
    https://clinicaltrials.ucsd.edu/opioid-use

    UCSD Opioid Use Clinical Trials for 2024 — San Diego

  15. Clinical Trials at UC Irvine
    https://clinicaltrials.icts.uci.edu/opioid-use

    UC Irvine Opioid Use Clinical Trials — Orange County, CA

  16. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915556

    Opioids and Chronic Pain: An Analytic Review of the Clinical …

  17. The New England Journal of Medicine
    https://www.nejm.org/doi/full/10.1056/NEJMoa2401177

    Community-Based Cluster-Randomized Trial to Reduce Opioid …

  18. Clinical Trials at UCSF
    https://clinicaltrials.ucsf.edu/opioid-use

    UCSF Opioid Use Clinical Trials — San Francisco Bay Area

  19. JAMA Network
    https://jamanetwork.com/journals/jama/fullarticle/2279713

    ED-Initiated Treatment for Opioid Dependence - JAMA Network

  20. PubMed
    https://pubmed.ncbi.nlm.nih.gov/33509278

    Core outcomes set for research on the treatment of opioid use …

  21. The BMJ
    https://www.bmj.com/content/377/bmj-2021-066375

    Efficacy of interventions to reduce long term opioid treatment for ...

  22. ResearchGate
    https://www.researchgate.net/publication/338233262...

    Clinical Trials for Opioid Use Disorder - ResearchGate

  23. The Lancet
    https://www.thelancet.com/journals/lancet/article/...

    Opioid analgesia for acute low back pain and neck pain (the …

  24. Springer
    https://link.springer.com/chapter/10.1007/164_2019_304

    Clinical Trials for Opioid Use Disorder - Springer

  25. Mayo Clinic News Network
    https://newsnetwork.mayoclinic.org/discussion/ai...

    Researchers explore potential for AI to predict patients' pain ...

  26. Food and Drug Administration (.gov)
    https://www.fda.gov/.../drug-trials-snapshots-omvoh

    Drug Trials Snapshots: OMVOH | FDA

  27. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK558319

    Treatment of Opioid Use Disorder - NCBI Bookshelf

  28. Nature
    https://www.nature.com/articles/s41593-024-01697-1

    Unlocking opioid neuropeptide dynamics with genetically encoded ...

  29. maine.gov
    https://www.maine.gov/governor/mills/news/opioid...

    At Opioid Response Summit, Governor Mills Urges Maine People …

  30. Medical Xpress
    https://medicalxpress.com/news/2024-07-opioid-disorder-infections.html

    Improving care for opioid use disorder through research into …

  31. Notre Dame News
    https://news.nd.edu/news/notre-dame-to-convene...

    Notre Dame to convene federal, state and nonprofit leaders to …

  32. Bloomberg
    https://www.bloomberg.com/news/articles/2024-07-18/...

    Non-Addictive Opioid Alternatives Are Coming But Won't Be …

  33. CBC
    https://www.cbc.ca/news/politics/the-opioid-crisis...

    The opioid crisis is hard to solve. Partisan politics isn't making it ...

  34. IndyStar
    https://www.indystar.com/story/opinion/2024/07/26/...

    Alternatives to PAIN Act gives seniors affordable opioid ... - IndyStar

  35. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497633

    Research approaches for evaluating opioid sparing in clinical …

  36. The News Journal
    https://www.delawareonline.com/story/news/2024/07/...

    Why Delaware's $50M in opioid settlement funds are now in limbo

  37. ScienceDaily
    https://www.sciencedaily.com/releases/2024/07/240717121032.htm

    Designing safer opioids | ScienceDaily

  38. NBC News
    https://www.nbcnews.com/politics/supreme-court/...

    Supreme Court blocks Purdue Pharma opioid settlement, …

  39. Gilead Sciences, Inc.
    https://www.gilead.com/news-and-press/press-room/...

    Full Efficacy and Safety Results for Gilead Investigational Twice ...

  40. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919636

    OPAL: a randomised, placebo-controlled trial of opioid analgesia …

  41. New York State Attorney General
    https://ag.ny.gov/press-release/2024/attorney...

    Attorney General James Secures $86 Million Multistate …

  42. New York Times
    https://www.nytimes.com/2024/07/21/nyregion/mobile...

    Could Mobile Methadone Clinics Help People Quit Fentanyl?

  43. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK605137

    Addressing the Opioid Overdose Crisis Through Better Data